Manchester United's Kevin Moran was given a red card for fouling Everton's Peter Reid in 1985, and Arsenal's JoseAntonioReyes received two yellow cards in 2005.
Uruguay international Forlan put Atletico ahead in the 29th minute from a cross by JoseAntonioReyes, while Argentina's Aguero doubled the lead on 65 with a low shot from 12 yards.
The Madrid side were trying to use playmakers JoseAntonioReyes and Maxi Rodriguez to open up Bolton but, more often than not, the brave Andy O'Brien and Gary Cahill were quick to block the supply.
The Spanish side decided to test their visitors from the whistle and it quickly became apparent that the Liverpool back four were not sure how to deal with ex-Arsenal man JoseAntonioReyes and Simao operating down the wings, with Jose Manuel Jurado playing just behind Forlan.