Ranking second behind Murphy is a newcomer to our list: Katherine Heigl.

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On the other hand, the female lead and love interest, Allison (Katherine Heigl), has great potential as a television reporter.

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Fate, however, has plans for Ben, who drunkenly sleeps with a bright, ambitious woman named Alison (Katherine Heigl) and gets her pregnant.

NEWYORKER: Knocked Up

"What it comes down to is -- may the best dress win, " said Chavez, whose clients include Rachel Bilson, Kristen Bell and Katherine Heigl.

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But the complications begin with a pair of beautifully nuanced performances -- Seth Rogen is Ben, Katherine Heigl is Allison -- and they proceed from the characters' essential selves.

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But rather than focus on what defines their success or inspires their work, the roomful of television reporters was looking for juicy headlines, particularly as they related to Katherine Heigl.

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But for now, studios are premiering smaller films like the romantic comedy Killers, starring Katherine Heigl and Ashton Kutcher, and the comedy Get Him to the Greek, featuring British comedian Russell Brand.

FORBES: With no blockbusters opening, "Marmaduke," anyone?