Salk's vaccine, developed in the 1950s, involved injecting a virus that was "killed, " while Sabin's vaccine -- which he worked on in the 1960s and which was administered orally -- contained a weakened version of polio.
The flu vaccine is comprised of killed or inactivated virus (three most likely strains of flu virus based on predictions from the previous flu season).
According to Forbes contributor Steven Salzberg, a whooping cough epidemic in California that has killed nine babies may be the result of the burgeoning anti-vaccine movement.