When a CEO is done in, often it's simply by a lack of business acumen that eventually catches up with him.

FORBES: Magazine Article

The third is the lack of entrepreneurs who combine technological expertise, business acumen and the sort of balls that, in 2006, reputedly let Mark Zuckerberg turn down Yahoo!'

ECONOMIST: Entrepreneurship and technology

Examples around the world suggest that financial capital alone may not be sufficient to spur effective entrepreneurship among people who may lack business acumen, a vetted opportunity, and a network of advisers.

FORBES: Social Entrepreneurship: The MicroConsignment Model

It was his reputation for efficiency and his business acumen which convinced the Colorado Party to name him as their presidential candidate, despite his lack of experience in politics.

BBC: Profile: Horacio Cartes