The home side had made the more enterprising and threatening start to the game, but it was the visitors who took the lead in 13 minutes.
Eardley cleared a Kyrgiakos header off the line at the other end but Liverpool were shocked as the visitors took the lead when Adam drove in a penalty after Johnson tripped Varney.
But after dismissing Surrey for 216 earlier in the day, the visitors' lead stood at 228 when bad light in the capital forced an early closure to play.
The heroes of Leinster's Heineken Cup semi-final win over Munster started the game en masse and after weathering a spirited opening from the visitors built an early lead in their final home game of the season.
Igor Semshov gave the visitors the lead in Cardiff late in the first half after being set free by Andrei Arshavin.
Unfortunately for Pompey, their 39-year-old England stopper carried such benevolence into his performance and gifted the visitors the lead in the 32nd minute.
Cayne Handley restored the visitors' lead in the 39th minute but Boston levelled within two minutes through Spencer Weir-Daley and took the lead five minutes after the break thanks to Marc Newsham's 16th goal of the season.
There was no surprise then when the visitors took the lead in the 20th minute.
Murray put the visitors into the lead in the third minute after taking a fine pass from Conor Walsh.
The nimble and tricky Osman had replaced the injured Steven Pienaar on the left of the Toffees midfield and it was his cross from which Johnson prodded into his own net to give the visitors a deserved lead as they notched their first away goal in the Premier League this season.
"I'm such a hugely proud policeman to be asked to lead the Met in bringing safety to millions of Londoners, millions of visitors and leading the Met's national efforts, " he said.
They did not have to win at Anfield but, after Meireles headed frustratingly over from a Dirk Kuyt cross, the visitors almost took the lead in fortuitous circumstances.
In a first 40 minutes that saw the Saints go in four penalties to two up, the visitors' lead might have been more.
But with Kallis and De Villiers adding 93 for the third wicket, the visitors must have been optimistic of forging a 2-0 lead in the series.
The struggling visitors took a seventh-minute lead through Sergio Floccari but goals later in the first half from Stefano Guberti and Giampaolo Pazzini were enough to give Samp the three points.
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However, Parks' sure-footed penalty gave the visitors a 15-13 lead in the 53rd minute.
The visitors took the lead after the break as in-form Robertson fired home a right-footed effort from Robson's cross.
Sexton's crucial try after 51 minutes gave the visitors an 11-point lead in what was a closely fought Pool Two clash at Wembley.
Two penalties from fly-half Dave Walder put Wasps 6-3 up, but the visitors took the lead for the only time in the match when replacement centre Marc Stcherbina cut through before laying-off a perfect pass for Smith to race in unopposed.
The visitors had taken a surprise lead in the 17th minute when Juanlu Hens latched on to a pass from Pablo Sicilia in the area and fired a low shot through the legs of Alberto Lopo and past Depor goalkeeper Daniel Aranzubia.
The lead only lasted seven minutes before former South Africa Under-21 international Oelschig kicked the visitors back in front and they led 14-13 at half-time.
It was heartbreaking for the Rams but a real shot in the arm for the visitors, who could have doubled their lead but for a brilliant double save from Carroll, first from Jenas and then Berbatov.
With seven minutes remaining, Carmont gifted St Helens a chance to take the lead when he dropped on the ball in an offside position and Foster's penalty put the visitors ahead.
The visitors thought they had doubled their lead in the 51st minute when McLeod, who continued playing despite having stitches in his calf, converted Christie's low cross.
It took Goode's second penalty to edge the visitors back into the lead but Contepomi soon levelled matters in similar fashion.
Although a Tickle penalty put the visitors in front, Leeds regained the lead when Donald collected Webb's long pass for his second score of the evening.
Montano's simple finish sparked more life into the hosts but the visitors still had the better chances and Wright-Phillips twice went close to adding to the lead in the final 30 minutes.
Michael Essien side-footed the visitors ahead before Nicolas Anelka added to the lead when he angled in a shot and poked in from close range.
Warrington were certainly not daunted by their high-flying visitors and went in at the break in the lead, as Fa'afili dived over to catch and touch down Lee Briers' kick into right-hand corner.
But because of their dominance in the middle of the park and the sheer volume of chances, Sunderland boss Steve Bruce must have been staggered and sickened in equal measure when the visitors took the lead five minutes after the break.
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