Lief was sold but figured he couldn't get venture capital to fund this unproved theory.

FORBES: Magazine Article

Shrugging off the past, Arena Pharmaceuticals Chief Executive Jack Lief thinks he has a new weight-loss pill that will work.

FORBES: Magazine Article

"Think of it as an opportunity to hot-wire any car in an airport parking lot without having the key, " says Lief.

FORBES: The Next Fat Pill

Jack Lief , Arena's chief executive, points out that the heart valve side effects were rare, and that a big clinical trial could settle the issue.

FORBES: Fat Chances

"I'm looking for an over-the-top kind of deal, " says Lief.

FORBES: Fat Chances

On a conference call, Arena Chief Executive Jack Lief said that there were heart valve problems seen in the trial, but that in the end he expects no difference between Arena's drug and placebo when it comes to this side effect.

FORBES: Magazine Article

Arena was founded in San Diego by Lief, a veteran drug executive with experience at Abbott and Cephalon, and researchers Dominic Behan and Derek Chalmers, who had both left San Diego biotech Neurocrine Biosciences to pursue novel ideas about drug development.

FORBES: Magazine Article

Arena was founded in San Diego by Lief, a veteran drug executive with experience at Abbott and Cephalon (nasdaq: CEPH - news - people ), and researchers Dominic Behan and Derek Chalmers, who had both left San Diego biotech Neurocrine Biosciences (nasdaq: NBIX - news - people ) to pursue novel ideas about drug development.

FORBES: The Next Fat Pill