Pfizer is also in the early stages of litigation over Lipitor with Teva in the United States.
And, Lipitor is the first of many blockbuster drugs to come off patent: e.g.
It still faces the mother of all patent expirations next year, when Lipitor loses its protection.
Better yet, it cut LDL, the bad cholesterol, by 18% more than Lipitor alone--a substantial decrease.
In the end, Pfizer doesn't really have a choice, given how big Lipitor will eventually be.
Patients either received the top dose of Pfizer's Lipitor or the second-highest dose of Bristol's Pravachol.
In these people, the combination of torcetrapib and Lipitor raised HDL 57% more than Lipitor alone.
And existing drugs, big sellers like Merck's Fosamax and Pfizer's Lipitor, are facing generic competition.
And some doctors have reacted coolly to the possibility of an OTC version of Lipitor.
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Late last year, Pfizer won a victory over one such challenge, from Ranbaxy on Lipitor.
Every major medical treatment from Taxol to Lipitor has its roots in NIH-funded basic science.
Meanwhile, Pfizer is facing a major battle if it is going to keep Lipitor growing.
Pfizer's Lipitor has easily held its ground against Crestor, which claims to be more potent.
Older drugs like Lipitor aim to prevent the cholesterol from ever getting to the arteries.
If that's true, many patients would be better off on Lipitor or Crestor than on Vytorin.
Pfizer's top seller, the cholesterol drug Lipitor, is the best-selling drug in the world.
LDL, the bad cholesterol, was cut 50% on Lipitor, compared with 41% on Zocor.
Bad cholesterol, or LDL, was cut 50% on Lipitor, compared to 41% on Zocor.
The target here, Lipitor, not only reduces bad cholesterol but also is effective in preventing strokes.
Whether peak annual Humira sales will ever reach the Lipitor benchmark is open to conjecture.
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He takes the drug himself, along with Lipitor, because he can't tolerate a higher Lipitor dose.
The combo also lowered the low-density, or "bad, " cholesterol 17% more than Lipitor alone.
In that study, Lipitor did not have the muscle side effects seen in this Zocor trial.
Zetia itself has become a blockbuster, and some doctors are prescribing it with Lipitor and Crestor.
Medicines such as Lipitor, Zocor and Pravachol cut down on heart attacks and save lives.
It shows Pfizer's Lipitor prevented heart problems better than a high dose of Bristol's own Pravachol.
If torcetrapib had worked, Pfizer executives had said it could be as big as Lipitor.
's Crestor has finally won a blow against Pfizer 's rival Lipitor, the world's best-selling pill.
What will happen after Nov. 30 when Lipitor patients try to get their pills?
In the meantime, even patients who might otherwise be switched to generics might keep receiving Lipitor.
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