They justify it by saying that feedback doesn't apply to them they aren't as likely to die before 60 as other people, for instance, because they have grandparents who lived into their 90s, or because they are avid gym goers with low blood pressure.

WSJ: Resolutions: So Irresistible, So Hard to Keep

Both groups lived about 16 months, and those on Avastin had more side effects mostly low blood counts, blood clots and high blood pressure.

NPR: Avastin Fails Studies In New Brain Tumor Patients