The results showed that lifestyle changes, such as a low calorie diet, exercise and a little help from a coach, were more effective in reducing the risk of developing diabetes than drugs.
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After six months, the non-diet group had lost an average of 1% of their weight, the calorie restriction group, 10.4%, those who were on a calorie restricted diet plus exercise, 10% and the very low-calorie diet, 13.9%.
"I would never recommend doing a very low-calorie diet alone, " says Hernried.
No one knows exactly why a low-calorie diet extends the life of mice, but some researchers think it is linked to the rate at which cells divide.
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The drug, which is based on a chemical found in red wine that is thought to mimic the life-prolonging effects of a very low-calorie diet, proved safe.
There was little change in micro-organisms present in the mice who had had sham operations, even though the group on the low-calorie diet lost just as much weight as the mice who had had the bypass surgery.
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For 24 weeks, the first group followed a low fat and calorie diet, exercised 150 minutes a week, and received counseling.
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People who have had obesity-related type 2 diabetes for years have been cured, at least temporarily, by keeping to an extreme, low-calorie, diet for two months, scientists report today.
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This is primarily due to competition from niche brands and increased health awareness among consumers that has favored the diet or low-calorie brands of competing players.
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They packed diet-friendly frozen meals for lunch and low-calorie snacks like yogurt, carrots and apples.
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