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The gala, which takes place in the Italian capital until 4 November, will open with Luc Besson's The Lady, a biopic of Burmese pro-democracy leader Aung San Suu Kyi.
BBC: Actor Richard Gere to collect Rome Film Festival honour
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In 2006, Farrow made a movie comeback, starring in three films released that year - a remake of The Omen, romantic comedy Fast Track and Luc Besson film, Arthur and the Minimoys.
BBC: Profile: Mia Farrow
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Its producer, Luc Besson, famed for films including Leon and Nikita, said he decided to remake the original film because he had loved it so much as a boy, and it had "emotional memories" for him.
BBC: Cruz minus Cruise at Cannes
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For those with a taste for political allegory, there is something to ponder here, although the director, Pierre Morel, together with his producer (and co-writer) Luc Besson, takes things at such a clip that little room is left for contemplation.
NEWYORKER: Taken