Despite the defeat, Querrey is certain to usurp John Isner as the U.S.'s top-ranked male tennis player.

CNN: Federer, Nadal to renew rivalry at Indian Wells

Querrey will usurp world No. 15 John Isner as the top American male tennis player after a 7-6 (7-5) 6-7 (7-9) 7-5 defeat of Australian 23rd seed Marinko Matosevic earned him a last-16 place.

CNN: Djokovic, Azarenka extend unbeaten runs at Indian Wells

The 31-year-old Federer has done it all in the world of tennis, winning more grand slam titles than any other male player in history and spending a record number of weeks at the top of the world rankings.

CNN: Hungry Federer eyes grand slam titles in 2013

Though likely not an attempt to be overtly jingoistic, the lack of a top American male player who consistently challenges for titles has hurt the level of corporate support in tennis.

FORBES: Has The PGA Tour Reached Its Financial Apex?