Dutch enforcer MarkvanBommel was booked after going through the back of Iniesta, while Nigel de Jong was lucky to escape red after planting his foot in the chest of Xabi Alonso.
Van Persie is not the only player carrying an injury to be included in Van Marwijk's squad, with Liverpool's Dirk Kuyt, MarkvanBommel, Khalid Boulahrouz, Wout Brama, Eljero Elia, Theo Janssen and Ruud van Nistelrooy also called up.