If researchers determine different metabolite levels are better, or examine a different metabolite to adjust the dose, there is no infringement.

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An expert for Prometheus said the patent covers any physician who determines metabolite levels in treating an autoimmune disease, and is aware of the ranges specified in the patent.

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The children's own metabolite levels were not linked to their IQs, however, which suggests that prenatal -- rather than childhood -- exposure is largely responsible for the trend, Eskenazi says.

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The 27-year-old Swiss player was found to have tested positive for a metabolite of cocaine while competing at Wimbledon last year, the ITF said in a statement published on its Web site.

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Even a researcher working on dermatological diseases, who determined that different levels of metabolite were appropriate, was threatened with suit because Prometheus suspected she had used their levels in her research, Singer said.

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The sample contained Benzoylecgonine, a metabolite of Cocaine.

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While the average metabolite levels of the pregnant women in the study were substantially higher than the national average, as many as 25% of pregnant women in the general population have levels above the study average.

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