Gate Pharmaceuticals, Mylan Pharmaceuticals, and Teva Pharmaceuticals have gained FDA approval for 300 milligram (mg) clopidogrel.
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The 80 milligram doses of simvastatin and Vytorin were prescribed 11.3 million and 1 million times, respectively.
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Not only is it non-sedating, but a 200-milligram dose is being tested for both men and women.
Barr gained a 180-day exclusivity, starting last August, to market a 20-milligram capsule generic version of the antidepressant.
Nissen of the Cleveland Clinic, compared the 80-milligram dose of Lipitor to the 40-mg dose of Bristol's Pravachol.
Now she takes half a milligram of Xanax twice a day, and 20 milligrams of Celexa at night.
To make things worse, the high, 80-milligram dose of the drug will probably not make it to pharmacy shelves.
"Ultra low tar" brands claiming to deliver just 0.1 milligram (mg) of nicotine, actually delivered closer to 1 mg.
"I'm selling enzymes by the milligram now, instead of the ton, " he chuckles.
Reporting in the journal Marine Drugs, the authors found BMAA concentrations ranging from 144 to 1, 838 nanograms per milligram.
Crestor still may find its niche: Milligram per milligram, it is the most powerful single-agent cholesterol pill on the market.
They also said the side effects were in line with previously known side effects for the top 80-milligram dose of Zocor.
Merck says only 12% of patients were taking the 80-milligram dose, however.
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According to the Guangzhou authorities, the contaminated samples were found to have 0.21 milligram to 0.4 milligram of cadmium in each kilogram of rice.
He also suggests that weaknesses in the FDA's surveillance of approved drugs may have let the risks of the 80-milligram dose slip by unnoticed.
That means the 80 milligram dose of simvastatin was prescribed more times than all doses of Vytorin, which was prescribed 8.6 million times last year.
FORBES: The Scary Thing About the FDA's Simvastatin Decision
John Alexander, global head of research at Daiichi Sankyo, says the FDA asked for an analysis of whether a lower five-milligram dose could help these patients.
Ranbaxy has reported that certain lots of their 10, 20, and 40 milligram tablets contain glass particles, bits that are smaller than 1 mm in size.
Generic drugmaker Ranbaxy Laboratories will make the biggest, 80-milligram dose, which is rarely used because of an increase in side effects with high doses of the drug.
Forest says clinical trials involving 1, 100 patients show that a low, 10-milligram dose of Lexapro is as effective at relieving depression as a 40-mg dose of Celexa.
The FDA said that 2.1 million people had been prescribed the 80 milligram dose, either by itself or in a combination pill like Vytorin or Simcor, last year.
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In a Canadian study with lorcaserin, such test subjects only found altered effects with the 40 and 60 milligram doses, four- and six times higher than the recommended dose.
But although the high, 80-milligram dose of Lipitor cut heart attacks compared to the 10-mg starting dose, the increased dose did not cut down on the total number of deaths.
Put one way, these refunds are no more than a milligram of a cure, when a full ounce of prevention over the last decade might have prevented a ton of pain.
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In a dose-ranging study presented at the American College of Cardiology in March, patients who received the top 120 milligram dose of ETC-1002 saw their LDL decrease by a still-respectable 27%.
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In one early test of the medicine, which must be injected, patients whose cholesterol was still too high on the 10-milligram dose of Lipitor had their Lipitor dose upped to 80 mg.
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In a letter sent to AstraZeneca, an officer at DDMAC noted that the efficacy of Crestor's top 40-milligram dose was similar to that of 80 milligrams of Lipitor in the study referenced by AstraZeneca.
Yesterday the Food and Drug Administration told doctors to stop prescribing the top 80-milligram dose of simvastatin, also known by the brand name Zocor, to new patients because of a heightened risk of muscle pain.
FORBES: The Scary Thing About the FDA's Simvastatin Decision
Since experimental evidence has suggested that antioxidants consumed orally, such as beta carotene, can reduce signs of sun-related skin damage, the study also looked at whether a daily 30-milligram beta carotene supplement could protect against skin aging.
In August U.S. drug regulators awarded Dr. Reddy's a so-called 180-day exclusive period for the 40-milligram generic version of Eli Lilly's Prozac, which had just come off patent (Barr Labs gained the license for the much-better-selling 20-milligram dosage).
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