Monoclonal antibodies are engineered versions of natural immune-system fighters that attack a particular target.
Instead, it focused on treating cancer with monoclonal antibodies, an approach that was highly unpopular at the time.
Both drugs are monoclonal antibodies that are supposed to attach to the amyloid protein and clear it from the brain.
That's when UCSD oncologist Ivor Royston and research assistant Howard Birndorf founded Hybritech to explore using monoclonal antibodies to fight cancer.
Bigner spent years trying to make monoclonal antibodies against the mutant protein.
Novartis hooked up with Schwab and has crafted monoclonal antibodies to Nogo.
For example, monoclonal antibodies target and kill tumors while sparing healthy cells.
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Today monoclonal antibodies are used to treat rheumatoid arthritis, transplant rejection, psoriasis, Crohn's disease, multiple sclerosis, macular degeneration and several types of cancer.
None of the majors are willing to invest big, the way that Roche did with Genentech decades ago when monoclonal antibodies were still controversial.
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She said using antibodies as 'magic bullets' had been clinically difficult, and the mTCRs were difficult to make and had all the same problems as monoclonal antibodies.
Stem cell therapies have the potential to surpass monoclonal antibodies because they use cells doing what cells normally do to stimulate the body to do what it normally does.
Monoclonal antibodies quickly gained popularity in research and diagnosis.
As with monoclonal antibodies, all it will take to usher in success is one breakthrough medical treatment, and it is highly likely such a breakthrough will occur within the next few years.
It has had a relationship with Akorn for three years to market injectable anticancer products and rabies monoclonal antibodies manufactured by Serum, and recently announced it was buying 2 million shares in its American partner.
If ImClone Systems ' (nasdaq: IMCL - news - people ) Erbitux failed a clinical trial, other monoclonal antibodies, such as Genentech 's (nyse: DNA - news - people ) Rituxan, wouldn't be thrown out.
Unlike chemotherapy, which uses chemicals to poison cancer cells, Rituxan's monoclonal antibody kills tumor cells much as the body's own antibodies kill invading germs.
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