Scrutinising the glass under a microscope (after treating it with appropriate chemicals) would make it clear if a monopole had turned up or not.
ECONOMIST: Magnetic monopoles: Absence of evidence | The
The path of a monopole would have a distinctive pattern lots of damage at the beginning of its journey and very little towards the end of it.
Although the grand prize of all this searching would be to find a monopole, a close second would be a conclusive result that they do not exist.
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