The mutation that causes blue eyes reduces the expression of OCA2 and hence reduces pigment concentration.
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They found a genetic mutation that seemed to indicate a bone marrow transplant was necessary.
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That's because most women don't have the mutation and because most breast cancer is sporadic.
That's important because women falsely diagnosed as a mutation carrier might undergo prophylactic mastectomy unnecessarily.
Oculocutaneous albinism type 1 is caused by a mutation in a gene on chromosome 11.
Oculocutaneous albinism type 2 is caused by a mutation in a gene on chromosome 15.
That meant the mutation was almost certainly on a gene on the X chromosome.
It was then restored with a stem-cell transplant from a patient with the mutation.
Beachy has turned normal prostate cells cancerous with a single mutation in Sonic hedgehog.
In mice, Fouchier said, the mutation makes the infection as much as 1, 000 times more virulent.
One concerning mutation, known as "Substitution Q226L, " was found in two of the first three victims.
The researchers suggest this kind of mutation could be how the prions cross between species naturally.
The trio published work in 1999 showing that they could increase the rate of HIV mutation.
The drug so far has only helped patients whose tumors have the BRAF mutation.
The problem: His leukemia cells contained a mutation that made them resistant to Gleevec's effect.
The mutation freezes a crucial protein called epidermal growth factor receptor in the "on" position.
Even before the mutation was identified, the woman had suspected she might be of crypto-Jewish origin.
The first step is to sequence the patient's DNA in order to uncover the cancer-causing mutation.
Then, instead of administering a one-size-fits-all drug, doctors would use one that addresses the specific mutation.
Resistance can arise due to a genetic mutation in bacteria which are normally susceptible to antibiotics.
Another question is why such a disastrous mutation should have spread so widely in Africa.
The good news is that this mutation is quite common, at least among westerners.
No light from a sample, therefore, means that that particular mutation is absent from it.
But those changes are not passed on indefinitely, like a successful genetic mutation would be.
Then test results showed that her tumor cells did not have the mutation that Tarceva targets.
Its researchers are studying families with a genetic mutation that triggers the early onset of Alzheimer's.
He specifically questions whether complex systems could have evolved gradually through natural selection and random mutation.
They carry the mutation for Tay-Sachs disease nine times more often than the general population.
For instance, some people, who have a particular genetic mutation, are immune to infection.
Both drugs are being tested in patients who have two copies of a genetic mutation called F508del.
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