Se-Jin Lee, the molecular biologist at Johns Hopkins University who discovered myostatin in mice in 1992, says it's "disappointing" that MYO-029 is dead, but he still believes blocking myostatin holds promise.
There have been drugs that previously showed promise in muscular dystrophy but failed: namely, MYO-029, a blocker of a protein called myostatin, was developed by Wyeth but then quietly discontinued after it failed to have a benefit.