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Princeton's Jacobs found that activating serotonin receptors in the (animal) brain aided in neurogenesis.
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Neurogenesis is a wonderful word that means our brains continue to grow new neurons throughout our lifetimes.
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In 2000 Yale's Ronald Duman found that numerous antidepressants, as well as therapies such as electroshock, boost neurogenesis.
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Animal studies have shown that stress damages brain cells to the point where it can inhibit neurogenesis (the growth of new brain cells).
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Dr. Seth Blackshaw, the lead researcher, comments that hypothalamic neurogenesis may be a mechanism that evolved to help wild animals survive and probably also our ancestors.
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Imaging studies on depressed humans show shrinkage in their hippocampus, a brain region involved in learning, memory and emotion that is also a region where much neurogenesis occurs.
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With time, neuroscience research uncovered two parts of the brain that evidence neurogenesis: the hippocampus, associated with memory formation, and the olfactory bulb, associated with the sense of smell.
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But when they became adults, the mice fed a high fat diet showed four times the neurogenesis of the normal mice, and gained significantly more weight and had much higher fat mass.
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Now, a study has uncovered a third part of the brain that, at least in mice, shows positive signs of neurogenesis: the hypothalamus, associated with body temperature, metabolism, sleep, hunger, thirst and a few other critical functions.
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The findings could have promising implications for diseases that involve a neurogenesis deficit -- in other words, a lack of new brain cells being born -- which happens in conditions such as depression, Alzheimer's and Parkinson's, the authors said.
CNN: How memories form, fade, and persist over time