Indeed, new drug development partnering virtually evaporated in 2002.
The wave of new drug development in myeloma dates to the late 1990s and early 2000s, when researchers were scouring old treatments for one that might have an impact on the cancer.
Given the great amount of time and cost needed to develop these drugs, innovating firms must be given adequate protections on data exclusivity to ensure they can recoup their investment and be able to continue with new drug development.
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Another new drug under development for lowering cholesterol in FH patients is lomitapide (Aegerion).
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"This is the first new drug-development platform in the post-genomic era, " beams Lanphier.
It is useful to set out the key steps in the argument as it applies to new drug and device development.
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Stephen O'Sullivan, the assistant general counsel for Pharmacia, says that the proposed changes would have a chilling effect on new drug research and development.
He said new drug treatments currently under development might provide an alternative.
There are eight new chemical entities in various stages of development that have generated four investigational new drug applications with the FDA. Since the payoff from these projects is far in the future, Ranbaxy's labs will continue pumping out generics, which net the company an aftertax margin of 16%.
But interaction of some sort is a prerequisite for the development of a new drug or a new use for an existing one.
The Hong Kong company aims to strike gold by expanding the global appeal of traditional Chinese medicines and by using modern drug development methods to unearth new drugs within Chinese medicinal herbs.
Much of the development cost of a new drug is paid by the US market (yes, this is why you pay higher prices than most Europeans do) meaning that as long as drugs in, say, Greece are sold at above the marginal cost of production they still make a profit.
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But it still said the rising costs of drug development and the increase in time in takes from to bring a new drug to the market remains an ongoing problem for the pharmaceutical industry.
The giants are starved for new blockbusters--last year had the fewest new drug approvals in two decades--and one-third or so of new products in development are protein drugs.
Legislation in these areas would threaten drug company earnings and discourage development of new products.
But for drug development, the promise of these new cells is likely to be too good for companies, Big Pharma and biotech alike, to pass up.
Furthermore, the FDA granted approval for these two new drugs quickly, which also reduced the costs of drug development.
It does not require a merger to plug the immediate gap between earnings and investor expectations by speeding up drug development cycles, improving stock management and launching new products simultaneously in many different markets.
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The current level of drug research and development offers hope for a wealth of new treatments that can mend and extend the lives of millions of people.
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Their way may be made easier by novel drug-development technologies, such as pharmacogenomics, and new marketing methods, such as e-commerce, which will allow them to sell tailored drugs without the trappings of size.
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The U.S. approved 33% more new cancer drugs than European nations including the United Kingdom, France, and Germany between 2000 and 2011, and approved them much faster as well, according to new research released today by the Tufts Center for the Study of Drug Development.
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The idea itself is not new--using existing molecules as a template is a hallmark of drug development.
But there appears to be only one new cholesterol-lowering pill in mid-stage development, and its a drug that Pfizer ate up and spit out.
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Although many of the genes encoding El Tor's pathogenic machinery were already known, the new sequence does reveal a number of unexpected metabolic pathways that may prove useful for drug development, according to Dr Mekalanos.
Cell Therapeutics said it intends to use net proceeds from the offering for general corporate purposes, including paying interest on or retiring outstanding debt and funding research and development, preclinical and clinical trials, and the preparation and filing of new drug applications.
The Obama administration has become so concerned about the slowing pace of new drugs coming out of the pharmaceutical industry that officials have decided to start a billion-dollar government drug development center to help create medicines.
The new test is the latest weapon in WADA's arsenal following the development of tests for the endurance-boosting drug erythropoietin (EPO) and so-called designer steroids such as tetrahydrogestrinone (THG), which have been chemically engineered to deceive the testers.
Now into this gloom comes a new type of drug, called an anti-CD3 antibody, that aims for the first time to delay or prevent development of the devastating disease by arresting the immune system's attack on pancreatic islet cells.
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