Dizzee Rascal and Deadmau5 will headline the event at Newcastle Gateshead Quayside on 3 and 4 June.
Ellie Goulding, Jake Bugg, Rudimental and Sunderland's The Lake Poets will also star at the Newcastle Gateshead Quayside on 26 and 27 May.
Last year about 40, 000 festival-goers led to almost 90% occupancy in hotels in Newcastle and Gateshead.
The guide's verdict on Tyneside has been welcomed the those behind the Newcastle and Gateshead bid for Capital Culture in 2008.
Newcastle and Gateshead councils, the Railway Heritage Trust, Electrical Contractors Association, Nexus, Go North East and Northern Electric and Gas have all helped to pay for the project.
All vehicles will run from the MetroCentre along the Tyne on the dedicated bus priority lanes currently used by the X66 CentreLink buses before heading into Newcastle or Gateshead.
BBC: NEWS | UK | England | Tyne | Park and ride to cut congestion
School leavers in the borough who want to take A-levels will now have to compete for places at three other sixth form sites or travel to neighbouring Newcastle, Gateshead or Sunderland.
Since 2009, Border's news bulletins have been presented from Gateshead near Newcastle.
The Tyne and Wear Metro was the UK's first light rapid transit system and serves the cities of Sunderland and Newcastle as well as Gateshead and districts of North and South Tyneside.
"The league games and the two cup games are going to totally different, " Gateshead boss Ian Bogie told BBC Newcastle.
Nick Forbes said Newcastle City Hall had "no long-term future" and a new venue would be built beside the Sage Gateshead.
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