The researchers conclude that nitric oxide activity may be impaired in people of Indian origin compared with whites.
Peroxynitrite, a reaction product of nitric oxide and superoxide radicals, has been implicated in N-methyl-D-aspartate receptor-mediated excitotoxic damage.
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Niteworks is made from L-arginine, an amino acid that helps produce nitric oxide.
Neurophysiologists have recently discovered that Nitric Oxide (NO) plays a vital role in many brain functions, including learning and memory.
Infants who received nitric oxide also tended to spend less time on the ventilator and required less time in the hospital.
The combination of exercise and supplements boosted levels of nitric oxide, which is known to protect the arteries and heart from damage.
"This finding may affect the relevance of trials involving cardiac, circulatory and neurologic disorders that are treated with nitroglycerin or nitric oxide-dependent therapies, " they said.
Aperon helped asthmatic people track a genetic marker called nitric oxide.
The researchers found that nitric oxide did not cause either problem.
It was found that nitric oxide was linked to a higher rate of brain haemorrhage in the most premature babies - 2.2 pounds (1, 000 grams) or less.
Previous research has indicated that a substance called nitric oxide, which is released from the endothelial cells, keeps the artery in good condition by stimulating the production of muscle in its wall.
David Field, professor of neonatology at the University of Leicester, said the US findings did not give the green light for using nitric oxide treatment, but were useful pointers to further research.
Nitric oxide effectively stops the platelets sticking together.
Although nitric oxide did not reduce the risk of all neurologic complications, only 12% of the infants who received it suffered a severe brain haemorrhage or tissue damage, compared to 24% of those who did not.
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