The top seven seeds receive a bye into the second round and the world No. 5 Juan Martin Del Potro made hard work of his place in the third round after a battle with Ukrainian Alexandr Dolgopolov.
So deep is the conference this year that the Bulldogs who own wins over top-ranked Gonzaga and No. 3 Indiana are seeded fifth and failed to clinch a bye.
The world No. 7, last year's runner-up to Amelie Mauresmo, has a first-round bye and will begin her title bid against Iveta Benesova of the Czech Republic or fellow Russian Anastasia Pavlyuchenkova, who meet on Tuesday.
The Orange lost three of their last four during the regular season, but earned a double-bye in the Big East tournament with a clutch 68-57 win over then-No. 13 Louisville in the season finale at the Carrier Dome.