It permanently blocks a key enzyme on the surface of the flu virus, stopping it from spreading to other cells.
Four of the genetic substitutions were in hemagglutinin, a protein on the surface of H5N1 that helps it to enter host cells.
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And, as a bonus, it is the protein that locks on to the surface of a host cell before the virus enters it.
In the 20 or so years I have been playing here at my home ground in Perth, I must admit I had never seen so much grass on the surface of a Test pitch and it was therefore no surprise to hear all the talk and prediction leading into the match.
Initial tests looking for "markers" on the surface of the bacterium showed it to be the O104 strain, which the World Health Organization said was rare, had been seen in humans before, but never in an outbreak.
The isolation cones placed strategically in a tripod pattern at the bottom corners of the sound system reduce the vibration frequencies and provide the most stable supporting structure regardless of the surface on which it rests.
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These data will provide invaluable information about Antarctic atmospheric dynamics, of the origin of water vapour over the oceans and how it is ultimately deposited as snow on the surface of the ice sheet.
It will fly for about 90 minutes before it runs out of fuel then it will make a graceful landing on the surface of Mars.
The art may appear on any writing surface even the rocky walls of cliffs but it is especially common on letters, scrolls, works of literature and fan coverings.
Instead, scientists believe that it "recruits" another natural protein, PrP, which sits on the surface of brain cells, to become like it.
Nasa's Curiosity rover has only been on the surface of Mars seven weeks but it has already turned up evidence of past flowing water on the planet.
"If anybody has been harboring doubts about the status of U.S. leadership in space, well, there's a one-ton, automobile-size piece of American ingenuity, and it's sitting on the surface of Mars right now, " said White House science adviser John P.
"This is a place that the whole world is watching, so of course it seems quiet on the surface, " said Nam, who guides tours to Panmungak.
No one bought into it, and the introduction of Surface makes blatantly clear that the "shove Windows 7 on a tablet and call it ideal" wasn't a real strategy.
Although the father's genetic material is present in the embryo and on the surface of the placenta, the mother's body does not reject it.
It is, however, an idea that needs to be carefully explained to the public, since on the surface the threat of important software being open to anyone seems greater than it being secret.
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To create the point-contact transistor, Shockley's team modified the cat's whisker by placing two fine metal wires close together on the surface of a germanium crystal, turning it from a diode into a triode.
NASA's Tom Rivellini joins us to discuss "seven minutes of terror, " and what it takes to land a rover on the surface of Mars.
Crowdsourcing will likely continue for some time, particularly in relation to the Super Bowl, because on the surface it seems like a good idea for a lot of companies.
Pyron uses an acrylic concentrating lens, which focuses the equivalent of the light from 6, 500 suns on a small optical device, which then spreads it across the surface of the solar cell.
On the surface, it is not the kind of corporate story that will entice investors.
The water was probably once on the surface and then percolated through the ground where it became trapped at a depth of 2.4km.
On the surface, it appears that the reaction of the mob came in response to a video produced by an individual or group in the United States.
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While the company has considered an inductive charging mouse pad, they opted against it so that people can mouse on the surface of their choice and to keep the whole package portable and inconspicuous.
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When the Viking lander 1 landed on July 20, 1976, it sent back the first pictures from the surface of Mars.
So it ought to be possible to test for the presence of a certain antigen on a surface by dragging a suitable antibody over it, and seeing if it gets stuck going fishing, in effect, on a molecular scale.
On the surface, it appears to be some sort of Wii peripheral, used to augment game experiences with an additional touchscreen.
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Although the temperature on Ascension has not changed appreciably in the past 30 years, sea-surface temperatures upwind of it jumped by more than a degree in the 1980s before levelling off.
Observations of the material coating the dark face of Iapetus indicate it has a similar composition to the surface material on Phoebe.
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