One of the biggest challenges of retirement planning is to estimate your future expenses.
"Food security is one of the biggest challenges we currently face, " said ABC's chairman Julian Little.
One of the biggest challenges is the requirement to keep from drifting more than 1, 076 square feet.
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One of the biggest challenges was figuring out how to integrate the ceramic electrolyte into the silicon.
One of the biggest challenges of this recession has been its impact on state and local communities.
One of the biggest challenges Paul has to overcome on a regular basis is his being a quadriplegic.
One of the biggest challenges was writing software to integrate ADS-B with an older, less sophisticated collision-avoidance system.
One of the biggest challenges that SMEs face is access to the financing they need to thrive and grow.
One of the biggest challenges for the solo-preneur is the lure of distractions.
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One of the biggest challenges Kindler faces is not merely operational but emotional.
This trial is a reminder of one of the biggest challenges facing Iraq: the challenge of holding the country together.
Joseph Ricketts, the billionaire founder of Ameritrade, has taken on one of the biggest challenges in baseball--owning the Chicago Cubs.
Second of all, the growing unaffordability of health care is one of the biggest challenges facing lower- and middle-income Americans.
One of the biggest challenges facing the aid industry is to create sustainable projects which can thrive without outsider financial support.
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And one of the biggest challenges for such companies is to make sure that they receive the financing that they need.
One of the biggest challenges for cash-strapped Pakistan is how to come up with the money needed to build the pipeline.
As anyone who has seen the incredible movie Apollo 13 knows, one of the biggest challenges of the mission was making course corrections.
"It's tough to tell a story when everyone knows how it ends, so that was one of the biggest challenges, " said director Dan Scanlon.
One of the biggest challenges is going to be convincing people they don't' need to feel guilty about coming to have a good time.
Balancing these consumer desires with a rapidly changing video landscape will be one of the biggest challenges for broadcast operators in the immediate future.
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One of the biggest challenges these prospective applicants will face is sorting through law school data and rankings which are oftentimes misleading.
"It is not just a challenge for Andy, it is one of the biggest challenges this group of players will ever have faced, " he said.
He added that one of the biggest challenges facing tablet makers in the U.S. is how best to sell the devices when they don't control the stores.
Anthony Salcito: One of the biggest challenges is the administration of such a large-scale initiative to meet the unique needs of individual communities in all 50 states.
This is one of the biggest challenges facing the field, and a big part of why, to date, no one in long-term cryonic suspension has been successfully revived.
This is one of the biggest challenges at Tides today.
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On the other hand, one of the biggest challenges that successive Japanese governments have faced is how to meet the huge social security costs engendered by an ageing society.
Like New Orleans, permanent housing is one of the biggest challenges Mississippi faces 24 months after Katrina, and the state estimates that 13, 000 families still live in FEMA trailers.
Years ago, I worked on Hurricanes Katrina and Rita recovery efforts in New Orleans, and one of the biggest challenges faced was effective, reliable and scalable communication systems during the crises.
"A lot of times the laws shape the culture, and one of the biggest challenges to breast feeding is culture, " said Ms. O'Connor, who also is a spokeswoman for the group.
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