Now, however, there are data showing some sign of heart risk for every Cox-2 inhibitor ever approved in the U.S. Vioxx doubled the risk of heart attack and stroke in one cancer prevention study, and now the same is true for Celebrex.

FORBES: Pfizer's Heart Attack

"Enzo is one of boxing's true gentlemen and he'd shown a tremendous amount of guts and heart to rebound from defeat and win the European belt, " added Haye, who defends his WBA heavyweight title on 13 November against British rival Audley Harrison in Manchester.

BBC: David Haye 'disgusted' at Enzo Maccarinelli knock-out