Do not miss the documentary Kusasi, From Orphan to King, about the campsite's most famous inhabitant.
In 1924, the comic strip "Little Orphan Annie, " by Harold Gray, made its debut.
Almost the entire burden of coping with the orphan problem falls on the extended family.
Parents (or would-be parents) typically want to adopt a healthy, young, orphan, usually a small baby.
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At the end of 2011, 1, 795 of those projects were aimed at orphan conditions.
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But before 1983, there were just 38 orphan drugs approved for use in the United States.
FORBES: The Lifesaving Promise Of The Pharmaceutical Drug Pipeline
As a result, the U.S. government offers special monopolies for drugs that treat orphan diseases.
Mr. Biswas is a 23-year-old orphan with a wife, a 3-year-old daughter and no formal education.
Bell plays orphan Smike in the film adaptation of Dickens' classic tale of friendship.
However, developing successful drugs for orphan diseases is not, of course, a slam dunk.
In the United States, HoFH, an orphan indication, occurs in approximately one in one million individuals.
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Without the Orphan Drug Act, there would probably be no Biogen Idec, no Genzyme, Alexion Pharmaceuticals.
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But the potential number of beneficiaries for each individual orphan treatment is relatively small.
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Without orphan-drug privileges at home, the richer European firms head to America to get them.
But Tercica has orphan status for its drug, which should protect Increlex from competition for seven years.
Gretel was taken to Redwings Horse Sanctuary in Norfolk and is now mothering orphan Shetland pony Lewis.
Moreover, approval was contingent on Orphan setting up a system that carefully controls who gets the drug.
One idea is to create an incentive for drugmakers comparable to that in the Orphan Drug Act.
This has become such a profitable pursuit that most drugmakers are pursuing at least one "orphan" drug.
That would allow Arena to target the hundreds of so-called orphan GPCRs that have no known ligands.
Instead they become, through no fault of their own, what the industry refers to as orphan accounts.
In the marketing of Xyrem, Orphan Medical pushed off-label uses for which there was no scientific support.
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An estimated 25 million people in the US alone collectively live with some sort of orphan disease.
AZT, began as an orphan drug for what was then an obscure disease of the immune system.
They trace the evil-plagued adventures of three orphan children while reading like a warped version of Harry Potter.
Insurers may want to avoid negative publicity and will pay for orphan drugs, assuming patient populations remain small.
The Orphan Drug Act was passed only because of the support of the National Organization of Rare Diseases.
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New orphan drugs are just one of the reasons that individuals with hard-to-treat diseases have reason to hope.
FORBES: The Lifesaving Promise Of The Pharmaceutical Drug Pipeline
In 1977, the musical play "Annie, " based on the "Little Orphan Annie" comic strip, opened on Broadway.
Google would also be given the right to digitise orphan works, titles where the authors cannot be found.
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