When he was 14, Zach was diagnosed with osteosarcoma, a type of bone cancer that mostly strikes children.

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Prior to the recent FDA action, Fusilev had approval for the treatment of osteosarcoma, a type of bone cancer.

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Recently the European Union approved MEPACT for use in pediatric patients with osteosarcoma.

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An athlete all his life, Howard was a distance runner for the University of California, Irvine cross-country team before a diagnosis of osteosarcoma and amputation of his left leg just below the knee.

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