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Avandia works by hitting a drug target called the peroxisome proliferator-activated receptor (PPAR) gamma.
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These receptors, the peroxisome proliferator activated receptors, or PPARs, come in three flavors, alpha, gamma and delta.
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Actos and potential successors such as Pargluva work on combinations of these genes, known as peroxisome proliferators activator receptors, or PPARs.
FORBES: Magazine Article
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Both Lopid and Tricor are thought to work by targeting a molecular signal called the peroxisome proliferators activator receptor (PPAR) alpha.
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These switches, called peroxisome proliferator activated receptors, or PPARS, have individually been the targets for both diabetes and heart disease drugs.
FORBES: Magazine Article
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They take aim at one or more of three emerging targets: These are peroxisome proliferator-activated receptors (PPARs), which are akin to master relay switches that control how the body uses sugar and fat.
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