The study showed virtually the same symptoms among mycoprotein eaters and a placebo group.
Not all of the placebo treatments that the researchers looked at in this study are inert.
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In IBS-C clinical trials, diarrhea occurred in 20% of patients vs 3% on placebo.
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Some patients might do worse than they would under a placebo, while others might do better.
It was found to elevate arousal 63% of the time, compared with 13% for a placebo.
The study involved more than 1, 800 patients who received either Vytorin or a placebo.
This study is actually the first of four placebo-controlled, Phase III trials to be completed.
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Viibryd also caused diarrhea in 28% of patients and nausea in 23%, both triple placebo.
In neither case was there a close to significant difference between Viibryd and placebo.
In trials among 2, 500 needle users in Thailand, placebo and vaccine will be divided evenly.
In a 10, 000-patient trial, more patients died on the Pfizer drug, torcetrapib, than on placebo.
Whether Amevive was the cause is unclear, but overall the drug was as safe as placebo.
My interest arose out of my early work on the placebo effect in chronic pain.
For all three studies, the placebo-adjusted percentage change from baseline at week 52 was statistically significant.
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One stumbling block: Coming up with a fake chocolate placebo that appears like the real thing.
The patients who began the study on placebo were switched to getting eteplirsen at 24 weeks.
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Clinical trials show that patients who took it had fewer relapses than those who received placebo.
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In the Crestor study, myopathy frequency was the same whether patients got Crestor or a placebo.
Among those who got placebo, 13.7% had one of those types of cardiovascular problems.
Those receiving Benlysta during clinical studies reported more deaths and serious infections compared with placebo.
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It only helped about a third of smokers--albeit a significant improvement over the placebo--quit.
Should doctors be liable if the placebo does not work, or can do a patient harm?
But whereas 4, 000 patients get Vytorin and another 4, 000 get placebo, only 1, 000 get Zocor.
Ethical considerations might require switching those patients on placebo to the drug, if Provenge is approved.
If the drug is approved, it may make it difficult to conduct that placebo-controlled trial.
There is no placebo group on the trial, and it involved only 102 patients.
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It was not placebo-controlled, blinded, or randomized, which presents major methodological problems regardless of what happened.
Snorting Adderall right before a test might raise scores because of a placebo effect.
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The added benefit of getting Botox over placebo was just about a day a month.
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And asking people to stay on a placebo for years on end poses significant ethical problems.
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