Eighteen percent of patients on KYNAMRO and 2% of patients on placebo discontinued treatment due to adverse reactions.
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Compared with placebo, treatment with Belviq for up to one year was associated with average weight loss ranging from 3 percent to 3.7 percent.
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Pain is another nerve-related symptom susceptible to treatment by placebo.
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This study randomly divided patients into two groups - one received the antibiotic and the other was given a placebo, an inert treatment in the form of a sugar pill, three times a day for seven days.
Safety data for KYNAMRO are based on pooled results from four Phase 3, randomized, double-blind, placebo-controlled trials with a total of 390 patients of which 261 patients received weekly subcutaneous injections of 200 mg of KYNAMRO and 129 patients received placebo for a median treatment duration of 25 weeks.
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However, these glowing results have a glaring weakness: They don't compare Velcade against a standard treatment or a placebo.
Or maybe a treatment will have "a placebo effect, " meaning it will make you feel better just because you have confidence it will make you feel better.
Rather, it found that although both forms of treatment were better than a placebo, there was no statistical difference between the results from the use of talk therapy and the popping of Lexapro.
The researchers found individuals with a COMT variant that triples the amount of dopamine in the front of the brain felt no improvement without treatment but an improvement with the placebo acupuncture.
VX-661 was generally well-tolerated, both as monotherapy and in combination with ivacaftor, and most adverse events were mild to moderate in severity and similar between the treatment groups and those who received placebo.
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Patients who received TSO treatment improved significantly more than those who got placebo.
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The most common adverse reactions in patients treated with KYNAMRO that led to treatment discontinuation and occurred at a rate greater than placebo were: injection site reactions (5.0%), alanine aminotransferase (ALT) increased (3.4%), flu-like symptoms (2.7%), aspartate aminotransferase (AST) increased (2.3%), and liver function test abnormal (1.5%).
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These new events were distributed equally between the three treatment groups (2.5 mg, 5 mg and placebo) of patients who were alive (806) and those who had died (37).
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The data monitoring committee overseeing the trial said patients were unlikely to benefit from the treatment, and identified higher adverse events in the subjects receiving the drug compares to placebo.
Patients who did not get Provenge did not receive a true placebo, but instead a sham version of Provenge followed by a frozen Provenge they could receive the treatment later on. (Provenge involves removing, altering, and replacing immune cells.) Patients who did get Provenge may have gotten placebo faster.
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