The study that proved Plavix's benefits contained twice as many patients as AtheroGenics' trial.
Lilly says that the risk validates its strategy of comparing prasugrel directly to Plavix.
He has been paid for work by the makers of both Plavix and prasugrel.
Some cutting edge thinkers insist that genetic tests could help doctors give Plavix more effectively.
Unlike vorapaxar, which is given in addition to Plavix, prasugrel is a Plavix competitor.
But Amusa insists that Sanofi isn't addressing important issues, such as the Plavix litigation.
Drugs like aspirin and clopidogrel (Plavix, NYSE:BMY) prevent platelets from clumping together into a clot.
Analysts generally expect Bristol and Sanofi-Synthelabo , which developed Plavix, to triumph, but they've been wrong before.
Anthony Ware, who leads Lilly's prasugrel team, says this market accounts for about 24% of Plavix sales.
Some estimates put the stent portion of the plavix market at less than 10% of Plavix sales.
Baraclude - After Plavix, Baraclude is the next significant challenge that BMS will have to face immediately.
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Bristol-Myers Squibb and Sanofi-Aventis are in the midst of a legal fight with Apotex to protect Plavix's patent.
The U.S. patents on its most famous products, notably Plavix for heart disease and Ambien for insomnia, have expired.
Eli Lilly 's most important pipeline drug is prasugrel, a Plavix-like pill being invented by Japanese drug giant Sankyo.
Unlike Plavix, prasugrel (brand name Effient) carries a bolded warning that it should not be used in stroke patients.
Apotex, the privately held generic drugmaker that is making the knockoff, said that Plavix generics hit the market today.
Plavix and Singulair both go off patent over the next couple years, ending the age of mass-market medicines completely.
The first setback came from the prospect of the expiration of one of its blockbuster anti-platetet drugs, Plavix, in 2012.
Industry executives are probably thinking back to the success of drugs such as Plavix and statins like Lipitor and Zocor.
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Prasugrel wasn't tested in the wide range of heart patients who get Plavix, which is sold by Bristol-Myers Squibb and Sanofi-Aventis.
In a letter to his employees, Bristol-Myers Chief Executive PeterDolanPeter Dolan argued that the Plavix mess is actually bad for consumers.
Sanofi now sells Ambien on its own, but Bristol-Myers Squibb (nyse: BMY - news - people ) markets Plavix.
The plan going forward is to initiate big studies to test whether SCH 530348 can prevent heart attacks on top of Plavix.
But just as a Plavix add-on, Veltri says, the opportunity is huge.
If Sanofi was going to buy Bristol, the time to do it was before the Plavix ruling and before Zimulti was deep-sixed.
In a letter to his employees, Bristol-Myers Chief Executive Peter Dolan argued that the Plavix mess is actually bad for consumers.
It prevented 145 more non-fatal heart attacks than Plavix, a 23% drop.
The Plavix patent expiry simply hit the business more slowly that expected.
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If the studies work out and the drug is approved, it might someday be tested to prevent first heart attacks, where Plavix failed.
Anticipating a court ruling in its favour, Apotex , a Canadian pharmaceutical firm, introduced a generic version of a bestselling drug, Plavix .
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