The pneumococcal vaccine, made by Pfizer, has resulted in dramatic drops in meningitis and pneumonia.
In the US, where an individual pneumococcal vaccine is given to children during the first 18 months, there has been a two thirds fall in the disease.
The donor commitments provide manufacturers with an incentive to build manufacturing capacity to produce the pneumococcal vaccine, which protects children against the leading cause of pneumonia, which in turn is the leading cause of death for children under age 5.
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Prevnar is referred to as PCV7 (for pneumococcal conjugate vaccine 7).
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The pneumococcal polysaccharide vaccine is for everyone 65 and up.
The first graph looks at what happened to cases of invasive pneumococcal disease when the vaccine was introduced.
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There is promise there, particularly in the lung cancer drug crizotinib, which is being submitted to the Food and Drug Administration, and to Prevnar, the vaccine against pneumococcal disease, which is being tested in adults.
But that may not be the case with Prevnar 13, a new pneumococcal 13-valent conjugate vaccine for older people (ages 50 and up) to prevent pneumonia.
There, 83, 000 patients have been randomized to receive either Prevnar 13 or placebo to see if the vaccine prevents cases of pneumococcal disease.
But in 2000 Wyeth scored a huge hit with Prevnar, the first vaccine for infants against pneumococcal bacteria, a common cause of pneumonia and ear infections.
It proved so effective, in fact, that fewer pneumococcal infections occur in people over 65 who have never gotten the vaccine, because the germs are no longer circulating.
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