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They work by inhibiting prostaglandin, a hormone-like substance that plays a part in signalling pain to the brain.
BBC: Pregnant women warned off painkillers
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Any potential effects of the prostaglandin drug might not show up.
FORBES: Magazine Article
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Merck said Zioptan is the first preservative-free prostaglandin analog ophthalmic solution.
WSJ: New Drug Approved to Treat Eye Condition
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Both Steve Nissen and Allen Taylor say little is known about the long-term effects of its flushing-blocker, which works by blocking a cell receptor called prostaglandin D2.
FORBES: Magazine Article
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One possible inflammation target is a fat called prostaglandin E2.
FORBES: Pharma Prophet
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If drug developers could better target their inhibitors farther down the prostaglandin chain, they might produce powerful drugs that could fight pain and avoid unknown, possibly fatal, side effects.
FORBES: Magazine Article
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Another possible drug target is the prostaglandin thromboxane.
FORBES
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This prostaglandin-producing enzyme is called cyclo-oxygenase (COX).
FORBES: Magazine Article