"This study can also inform the rational design of novel strategies to counteract IgG4 actions, " he added.

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Rational drug design, the hallmark of new-school biotech, is no panacea, as Gladwell rightly points out.

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The drug was originally developed as Imatinib using rational drug design after Philadelphia chromosome mutation was discovered.

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But the court upheld a requirement for commercial interior design, holding that the state had a rational basis for protecting the public from inept design, which could create safety hazards.

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