Dr. Brentjens and a fellow co-author hold a patent on the engineered T-cell receptor.
Acomplia blocks the cannabinoid cell receptor famous for giving pot smokers the munchies.
Dr. Brentjens and a co-author hold a patent on the engineered T-cell receptor.
Furthermore, recent data suggests that IRAK4 inhibition synergizes with inhibition of other B-cell receptor signaling pathways, like BTK ( here).
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Both Steve Nissen and Allen Taylor say little is known about the long-term effects of its flushing-blocker, which works by blocking a cell receptor called prostaglandin D2.
Like a key in a lock, EGF binds to a receptor on a cell's surface, sending off a signal to the cell to divide, grow and die.
People with celiac disease usually have a certain type of cell surface receptor that helps set off the immune reaction.
HINT, crops up in 11 different genes for receptor proteins that sit on a cell's surface waiting for messenger molecules from other cells.
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Eventually, he began to study an antibody called Ibalizumab that was designed to block HIV from attaching to CD4, the primary receptor used by the virus to infect a cell.
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Even more surprisingly, they found that each receptor, located on the surface of a particular cell, is unique, and when activated by an odorant, triggers the cell to send an electrical signal to the brain.
But gp120's innards are exposed for 30 minutes or so while the protein is hooked to its human receptor, called CD4, in preparation to invade a cell.
The transferrin binds to its corresponding receptor, allowing the diphtheria toxin to enter into the cancer cell and kill it.
When EGF docks on a receptor, it signals to an enzyme called tyrosine kinase to regulate cell growth.
Lapatinib, it turns out, also inhibits the activity of a protein called the epidermal growth factor receptor, which has been found to be important for stem-cell proliferation.
Now entering human trials, it blocks a newly discovered receptor known as H3, the third in a family of crucial cell-surface proteins that receive messages from the hormone histamine.
Sometimes it is a normal gene that directs the production of a hormone, such as insulin, or of the cell machinery which that hormone stimulates, such as the insulin receptor.
This will be useful because the location and activity of receptor proteins on surface membranes can be a matter of life and death for a cell or a virus.
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