Both pills inhibit a receptor for a protein called the epidermal growth factor (EGF) that many tumors seem to depend upon to grow.

FORBES: Magazine Article

All three drugs target the epidermal growth factor receptor (EGFR), a protein that is over-expressed in cancer cells.

FORBES: Magazine Article

One such protein, the glutamate receptor, has been put under the control of a photoswitch and introduced into the retinas of mice.

WSJ: What Might Innovation Award Winners Look Like in Five or 10 Years?

His lab showed this protein to be the receptor for VEGF, and that blocking the receptor stunted the growth of tumors in lab animals.

FORBES: Targeting Tumors

The mutation freezes a crucial protein called epidermal growth factor receptor in the "on" position.

FORBES: Taking Aim at Brain Cancer

PCBs do their damage by binding to a protein called the aryl hydrocarbon receptor, or AHR, thus stopping it working properly.

ECONOMIST: Pollution and evolution

The public has mostly focused on Erbitux's ability to slow tumor growth by blocking epidermal growth factor receptor, a key growth-promoting protein that is overabundant in many cancer cells.

FORBES: Bristol, ImClone File On Erbitux

But gp120's innards are exposed for 30 minutes or so while the protein is hooked to its human receptor, called CD4, in preparation to invade a cell.

FORBES: Outsmarting AIDS

Lapatinib, it turns out, also inhibits the activity of a protein called the epidermal growth factor receptor, which has been found to be important for stem-cell proliferation.

ECONOMIST: Cancer therapy

While Sugen targeted the receptor for VEGF, Genentech was focusing on the protein itself.

FORBES: Targeting Tumors

The fragile X symptoms disappeared, suggesting that drugs that blocked the receptor--and thus reduced the amount of protein produced--might do the same thing.

FORBES: Magazine Article