The current face transplant patient understood the risk of rejection and of immunosuppressants, doctors said.
But there is a chronic shortage of donor organs and a high risk of rejection after transplantation.
Taking donor cells from a close relation reduces the risk of rejection of the transplanted cells by the recipient.
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He said it was important that cells could be tailored for each patient so there would be no risk of rejection.
The breakthrough could lead to patients creating their own replacement organs without the risk of rejection, a common complication in transplant procedures.
They found a 13% lower risk of rejection - where the body recognises the new heart as "foreign" and attacks it - in matched transplants over the first year.
They suggested that it might be possible to overcome the risk of immune rejection of the donor cells in humans.
If pigs could be genetically modified to reduce the risk of organ rejection, it might be possible to use their organs for permanent transplants, not just temporary ones, many scientists believe.
Because these cells would essentially be clones made from the patient's own cells, there would be no risk of the rejection problems typical with organ transplants, and therefore no need for the drugs that prevent the immune system from attacking a transplanted organ.
The hope is that the benefit of a lower rejection risk will outweigh the extra cost, as it may make the treatment more widely available.
Perhaps even more important, at least in the short-term, is Greece re-emerging as the primary risk-factor within the widening Euro-crisis, by there resounding rejection of the Euro-centric, pro-bailout incumbents in favor of anti-bailout parties.
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