And Calzaghe believes in Roy Jones Jr he is also fighting one of the greats of the sport.
The other was in 2000 when Roy Jones Jr. retained the light heavyweight championship against David Telesco in 2000.
Calzaghe victims include Chris Eubank, Robin Reid, Richie Woodhall, Charles Brewer, Jeff Lacy, Mikkel Kessler, Bernard Hopkins and Roy Jones Jr.
The boxer's defence concludes Sports Network "has no contractual right" to promote the Roy Jones Jr fight which Calzaghe has arranged for 8 November.
Calzaghe has, like Froch, enjoyed a superb 2008 as he beat American pound-for-pound greats Bernard Hopkins and Roy Jones Jr in the United States.
The judges scored it 120-109, 119-109 and 118-110 for Hopkins, who had been planning to take on old foe Roy Jones Jr in his next fight.
And while we're at it, Joe Calzaghe's prize-fighting farewell against Roy Jones Jr in New York City's iconic venue is not a world title fight either.
But the Welshman, who will fight Roy Jones Jr at light-heavyweight on 8 November, warned that the 22-year-old still had a lot to learn in the sport.
He twice defended the belt - including a draw with Holyfield in a rematch the same year - before losing it to Roy Jones Jr in 2003.
Two-weight world champion Calzaghe, who defeated American legends Bernard Hopkins and Roy Jones Jr in his last two fights, retired from a stellar 15-year unbeaten career in February.
Sixteen years later Roy Jones Jr. handed out a pummelling to Korea's Si Hun Park at the 1988 Games in Seoul only to rewarded with a silver by the judges.
The 2007 BBC Sports Personality of the Year's proposed New York showdown with American legend Roy Jones Jr in November will probably be his last and Calzaghe is promoting it himself.
Which might explain why, despite dazzling on the world stage for the best part of two decades and winning world titles at four different weights, there are those that question Roy Jones Jr's greatness.
Johnson's win over Woods saw him claim the vacant IBF title, which he defended against Roy Jones Jr in September 2004 before relinquishing it to fight the division's other main protagonist, America's Antonio Tarver.
Calzaghe's hunger to compete will also give him an edge, especially because the champ has not been a contender since November 2008, when he beat Roy Jones Jr at Madison Square Gardens in New York.
His stylish points victories over American boxing greats Bernard Hopkins and Roy Jones Jr in their own back yards have been rewarded with a place on this year's BBC Wales Sports Personality of the Year shortlist.
Radio City is a far more intimate setting, with a seating capacity of roughly 6, 000, and the venue has not hosted a fight since Roy Jones Jr. defeated David Telesco there in a light heavyweight world championship bout in 2000.
Calzaghe - who had won the award three times previously - cemented his place as one of boxing's all-time greats by stepping up from the super-middleweight division he ruled for more than a decade to beat American greats Bernard Hopkins and Roy Jones Jr at light-heavyweight.
Joe Calzaghe - who has won this award the last two years - cemented his place as one of boxing's all-time greats by stepping up from the super-middleweight division he ruled for more than a decade to beat American greats Bernard Hopkins and Roy Jones Jr at light-heavyweight.
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