The court heard the then nine-year-old Shannon had been given the sedative drug temazepam for up to 20 months before her disappearance.

BBC: Wetherby to Waco - DNA lab's demise

She said Polanski plied her with alcohol and quaaludes, a sedative hypnotic drug, during a photo shoot at the Hollywood Hills home of actor Jack Nicholson.

CNN: Decision on Polanski extradition due early next year

Indeed, its addictive effects, in terms of new neuroscientific discoveries, actually turns out to be a kind of drug or sedative.

CNN: SHARE THIS

His lecturer, Dr Geoff Case, had earlier met with Dr Geoff Shaw, an intensive care specialist at Christchurch Hospital, who had told him about the inherent problems in managing critically ill patients' sedative and pain relief drug dosages.

CNN: Device to save hospitals billions

Detective Orlando Martinez of the Los Angeles Police Department detailed what Murray told detectives he gave Jackson on the final day of his life, which included the sedative Valium (diazepam), the anti-anxiety drug Ativan (lorazepam), the sedative Versed (midazolam), and 25 mg of propofol.

CNN: Drugs that killed Jackson for clinical use only, experts say