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It blocks a signaling pathway called mTOR that appears to play a role in proliferation of several cancers.
WSJ: Breast-Cancer Drugs Raise Hopes
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After analyzing the data, the Wake Forest Baptist researchers identified the cell signaling pathway by which epinephrine, a hormone also known as adrenaline, sets off the cellular chain reaction that controls cell death.
FORBES: New Study Shows How Stress Feeds Cancer Cells
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He had found with a collaborator at Johns Hopkins that stem cells in mice genetically altered to have a similar disease did not respond normally to a signaling pathway called hedgehog that had an important role in brain development.
FORBES: Magazine Article