This is a historically significant development for those of us who track cyber espionage.
Mr Willetts described the centre as "the most significant development in British biomedical science regeneration".
The most significant development has been the absorption of the company, previously independent, into the Kennedy Center administration.
Nonetheless, one potentially significant development on the international front is the new tone in French pronouncements on Algeria.
The passing of a right-to-work law in Michigan is a hugely significant development.
One significant development in the third quarter numbers is that government spending increased for the first time in several quarters.
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If this is true, and there's good reason to believe that it is, then it would be a significant development.
This can save automakers significant development time and cost by enabling rapid implementation of in-vehicle systems across diverse vehicle models.
In what is surely a significant development, for the first time, one party commanded support of a majority of poll respondents.
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But the addition of the Ram 1500 with a 3.0-liter, V-6 EcoDiesel engine in the third quarter is a significant development.
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This is a significant development at the yield on the bond is one of three major inputs to the www.
Once completed, the 26-acre Related Hudson Yards will become of the most significant development projects in the U.S. since John D.
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"The really significant development over the past year lies elsewhere, " he said.
This is a significant development and shows leadership by the EU, whose politicians have acknowledged that an aggressive biofuels policy has backfired.
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"A highly enriched uranium test would be a significant development, " he said.
The Hawija incident was a significant development in the months-long protest movement in the Sunni cities in Iraq, the BBC's Baghdad correspondents says.
He cautioned that the mambalgins worked by injections into the spine so would need "significant development" before they could be used in people.
And I think that is the most significant development of the past 24 hours, in terms of an indicator of where this is headed.
The recently-concluded deal between Exxon Mobil and Rosneft has, as with any significant development in Russia, led to an awful lot of confused Kremlinology.
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"This time the emergence of two powerful parties with distinct political colors is a significant development in Korean politics, " says political scientist Cho Ki Sook.
Another significant development in 2008-2009, as noted in the report, is that the percentage of murders not linked to conflict situations considerably increased compared to 2006-2007.
"I hope tomorrow when we meet other countries we'll follow that through and this is a very significant development, the first time it's ever been done, " he said.
The awards honour women contributing to significant development in technology.
Coriolis and Falck said the project avoided protected areas and the site was close to other "significant development", including industrial estates at Evanton and a line of electricity towers.
In what could be a significant development, General al-Saadi said during the news conference that an Iraqi scientist had just sat down for an interview without government monitors present.
This was a very significant development for AMD that exposed the internal problems and weighed on the share price as the search for new CEO stretched longer than many expected.
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Chinese Estates, which owns and operates many shopping centers in Hong Kong, said it would make further announcements "if and when there is any significant development" in respect to the Macau land.
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"The teams will be adversely affected by any further significant development at the Meadowlands that interferes with fans' and patrons' ease of access, " stated the 27-page complaint filed in Bergen County Superior Court.
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Now, experts are beginning to recognize that the Affordable Care Act may, in fact, be contributing to the good news a significant development as bending the cost curve was a primary goal of Obamacare.
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Undoubtably Harlem Shake has sold a bunch of downloads since the meme took off, but most people have only heard the first 30 seconds, and the rest of the tune adds no significant development.
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