Williams has enjoyed huge success at the All England Club in the past, having won five singles titles and four doubles crowns at the prestigious grass-court venue.
The 26-year-old will take to the court on Tuesday for a doubles match, then start his singles campaign the following day after receiving a first-round bye as the top seed in the draw despite slipping to fifth in the world rankings.
And once the bitter sting of defeat on Centre Court had subsided, Federer insisted finally getting his hands on a singles medal tempered the disappointment of his straight-sets loss.
The match was the longest Wimbledon men's singles final ever at four hours, 48 minutes, and the winning shot was struck with Centre Court in near darkness at 2115 BST.