Liz Luff, from the Sir Bobby Robson Foundation, said the donation was the largest it had made.
Soap opera stars, the son of the late Sir Bobby Robson and chef Gordon Ramsey were also taking part.
Professor Ruth Plummer, a Cancer Research UK clinician at the institute who treated football legend Sir Bobby Robson, is helping to run the trial.
It would make McClaren the first English manager to win a major European league since Porto won the 1996 Portuguese title under Sir Bobby Robson.
IPSWICH, England -- Former England manager Sir Bobby Robson was taken to hospital after becoming ill while watching his former club Ipswich Town on Saturday.
The Newcastle United legend is the latest football star to sign up for a one-off match to raise funds for Sir Bobby Robson's cancer charity.
Sir Bobby Robson is reuniting players from the 1990 World Cup squad for a one-off match against West Germany, to raise money for his cancer charity.
And speculation has followed that Irons or director of football Mick Wadsworth - Sir Bobby Robson's assistant with England and Newcastle United - would be in charge next season.
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Shearer also paid tribute to another former Newcastle United manager, Sir Bobby Robson, who died last month, and under whom Shearer played at St James' Park for five years.
"I have spoken to Alex and Walter lately and to Sir Bobby Robson, who is a legend all over the world and managed England for a time, " he said.
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Sir Bobby Robson claimed Gazza was as "daft as a brush" and his immature behaviour and naivety was excused because it was seen as central to his desire to be the subject of the attention and affection he craved.
He then went on to become Ruud Gullit's assistant at Newcastle and had a brief spell as caretaker manager at the Tyneside club after the Dutchman's exit in August 1999 before working under Sir Bobby Robson at St James' Park.
He went on to become to become Ruud Gullit's assistant at Newcastle and had a brief spell as caretaker manager at the Tyneside club after the Dutchman's exit in August 1999 before working under Sir Bobby Robson at St James' Park.
The former Leeds and West Ham defender follows in a long line of Manchester United captains who have gone on to lead their country such as Gary Neville, David Beckham, Bryan Robson and Sir Bobby Charlton.
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