In these pre-vaccination days, smallpox pustules would be lanced, and their contents inserted into the skin of healthy people, producing a (hopefully) minor, localized infection which would then protect people from severe smallpox infection.
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Psoriatic skin tries to repair itself by generating new cells, but it does so seven times as fast as healthy skin.
In a cruel twist, the body's disease-fighting T cells attack healthy skin cells, misidentifying them as foreign.
And the demarcation line between the affected and the healthy skin is remarkable.
This may eventually increase knowledge of the role of different genes in the maintenance of healthy skin - and in the growth of cancers.
If you have psoriasis, however, the T cells attack healthy skin cells by mistake, as if to heal a wound or to fight an infection.
The balloon has been filled with a special gel at the rate of six teaspoons full each week - with the healthy skin and hair stretching around it.
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With their new laser in hand, Dr Leitgeb and his colleagues set up an experiment that let them test the system on a range of skin conditions, including a healthy human palm, allergy-induced eczema on the forearm, inflammation of the forehead, and two previously diagnosed cases of basal-cell carcinoma.
When a person feels confident, healthy, happy and grounded in their own skin and within their personal brand, the world will most typically take note and respond.
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Lupus is an autoimmune disease characterized by inflammation of the joints, skin, major organs and central nervous system as the immune system attacks healthy tissues and cells.
Doctors say grapeseed oil is a healthy oil for cooking and a good moisturizer, but there is scant evidence that it keeps skin looking youthful.
The findings, reported in papers published by Nature and the Public Library of Science, were based on samples from 242 healthy volunteers in the U.S., from such sites as the mouth, nose, skin, intestine and vagina.
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