There are many other design-thinking principles that entrepreneurs need to heed, such as the fact that products and services are bought by human beings, not target markets segmented into demographic categories.
Firms like GeneSoft and Vicuron are taking things a step further, entering the earliest stages of human testing of drugs that target genes older antibiotics overlooked.
At the conference, the Alzheimer's Association International Conference on Alzheimer's Disease, two companies, TauRx Therapeutics from Singapore and Allon Therapeutics of Vancouver, presented human trial data for drugs that target tau.
The new U.S. strategy also calls for a more aggressive diplomatic response to the theft of trade secrets, much of which is now done by infiltrating computer networks of target companies but some is also still done by recruiting human spies.
Typically, these are motivated by a conspicuous success, a development program that was driven by the strength of beautiful molecular data, and the canonical example these days is PCSK9, a target which seems to feature an almost unprecedented alignment of human genetics, biomarker, and animal model data.
The government has had some success targeting primary pollutants, but analysts say it is just beginning to target secondary pollutant problems, including particulate matter that is harmful to human health.
The book is a polemic, and its main target is what Mr de Waal takes to be a distorted idea of human life as relentlessly selfish and ruthlessly competitive.
But the report's authors warn that even if this target to mitigate warming is met, "substantial impacts on society, human health and ecosystems are projected to occur".
By being too eager to meet a target or deadline the inexperienced manager does not allow a subordinate the autonomy that the human brain needs.
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McDonald suggests one likely target: Albuferon, an interferon drug for hepatitis C now in phase 2 trials that belongs to Human Genome Sciences.
Ribosomes are a key target for antibiotics, as antibiotics are able to attack the ribosomal activity of harmful bacteria while leaving human ribosomes untouched.
McDonald suggests one likely target: Albuferon, an interferon drug for hepatitis C now in phase 2 trials that belongs to Human Genome Sciences (nasdaq: HGSI - news - people ).
Most drugs would have been lost in the shuffle, but Velcade had two advantages: strong data in human beings, and the enthusiastic Adams, who has since become Millennium's director of target discovery.
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