Nintendo has sold over 145 million units in the DS line since 2004, making it the best-selling portable in history.

FORBES: Nintendo 3DS Could Be 2011's Most Important Gadget

Last year he co-starred with Gwyneth Paltrow in the film Country Strong and he has a line of best-selling colognes.

FORBES: Country Music's Highest-Paid Stars

Oracle, notably, is finally selling its Fusion line of software that promises to be the best of the old stuff with the ease-of-use of the new.

FORBES: What Workday's IPO Success Says About Software

As the site - and their visibility - has grown, the Petersiks have been able to supplement their revenue through projects like a best-selling book and a lighting line.

BBC: One couple's mission to find a better work/life balance

When Cisco bought Flip-maker Pure Digital, in 2009, the line of ultra-small, ultra-simple-to-use Flips were the best-selling camcorders on the market.

FORBES: Flipped Off: The Cisco Story

Famous for its globally best-selling HD HERO line of wearable and gear mountable cameras, GoPro spared no expense developing the HD HERO2.

ENGADGET: GoPro launches HD Hero2 helmet cam, announces video streaming Wi-Fi pack for winter

The self-taught, Mexican-born dog trainer has parlayed his talent for calming even the most vicious of dogs into a hit TV show, a series of best-selling books, and a mass market line of collars, leashes, beds and pet food.

WSJ: Me & My Brand: Lively Entrepreneurs Ring Up Sales