The third, fourth and fifth-ranked Heineken Cup group runners-up will play in the Challenge Cup quarter-finals.
Agar guided Hull to the Challenge Cup final at Wembley in 2008 with an injury-ravaged squad.
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Wayne Godwin, Terry Newton, Joe Vagana and Ben Jeffries also crossed as the Challenge Cup finalists crumbled.
Monaghan's drop-goal and another late converted try from King capped a resounding win for the Challenge Cup holders.
They were also knocked out of the Challenge Cup at the fifth-round stage by Super League rivals Wigan.
Panthers are next in action on Wednesday night when they travel to Cardiff in the Challenge Cup (1930 BST).
He has played with Wigan his entire league career, winning the Challenge Cup in 1993 and Super League in 1998.
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Wigan exacted vengeance on Hull for knocking them out of the Challenge Cup with a thrashing in the Super League.
In another change, the winners of the Challenge Cup will also secure an additional Heineken Cup qualifying place for their country.
It is presently without a sponsor for the league and its knock-out competition, the Challenge Cup, after Bell's withdrew in 2006.
He returned to Headingley to coach the Rhinos in 2001 steering them to the Challenge Cup final in Cardiff in 2003.
The Wildcats have won just two of their last six Super League games and also been knocked out the Challenge Cup.
The visitors also included Michael Lawrence at centre from the team that demolished Hull KR 40-12 in the Challenge Cup last week.
Wigan's win will be a real boost for the Warriors ahead of the Challenge Cup semi-final contest between the two sides next month.
That the Challenge Cup title came against one of the newly enriched elite of French rugby makes the achievement that much more impressive.
Aston is upbeat for their opening league game after picking up an emphatic 82-0 win over Leeds Met University in the Challenge Cup.
Millward was suspended on Wednesday over allegations of swearing and was not at the Challenge Cup fifth round match, which Saints won 62-0.
He will now be available for Friday's Super League clash with Catalans Dragons and the Challenge Cup fourth-round tie with Saints on 5 April.
But, from a personal point of view, I love the Challenge Cup and have never been this far with any club, so I'm buzzing.
The Dragons, though, lost, to Overmach Parma in 2006 and that was the only occasion a Welsh region has featured in the Challenge Cup.
The Heineken Cup final takes place in Cardiff on 21 May, with the Challenge Cup final the night before, also in the Welsh capital.
Panthers also picked up their second win in the Challenge Cup at the weekend, winning 4-2 against an injury and suspension-hit Hull Stingrays on Humberside.
"We're playing against one of the best teams in the competition, they beat Featherstone and had a comfortable win in the Challenge cup aswell, " he said.
Pontypridd are the only other Welsh side to qualify for the Challenge Cup final - Europe's second-tier tournament - which they lost to Sale 25-22 in 2002.
Brown guided the Giants to third place in 2009, in his first season in Super League, as well as leading his team to the Challenge Cup final.
Molin spent two years at the National Ice Centre, scoring one of the goals as Panthers won the Challenge Cup in a two-legged final against Sheffield in 2008.
There was a crowd of 84, 241 for the first final back at Wembley in 2007, while the last 'full house' for the Challenge Cup Final was in 1997.
His departure comes at a difficult period for the RFL, as they wait to discuss the pitch invasion which occured after the Challenge Cup semi-final between Hull and Leeds.
Less than 10, 000 spectators watched Northampton beat Bourgoin in the Challenge Cup final last year compared to the 66, 523 who saw Leinster overcome Leicester at Murrayfield in the Heineken Cup.
They go to the south of France again this weekend in the Challenge Cup still smarting from Sunday's defeat at Castleford, though Langley insists the players are far from downbeat.
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