Acute (short-term) inhalation exposure to high levels of 1, 4-dioxane has caused vertigo, drowsiness, headache, anorexia and irritation of the eyes, nose, throat, and lungs in humans.
FORBES: Responsible Investing: Is Pall 'Leading' in Water Filtration? (Governor Snyder's Hometown has a 1,4 Dioxane Problem)