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With Fuga off the pitch and unavailable to throw in at the line-out, Northampton stole a Quins throw and Downey raced clear to give the hosts the lead.
BBC: Northampton 23-13 Harlequins
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The northerners were on terms by the 16th minute as Humphreys notched a clever try by running to grasp his own dinked kick over the Munster defence after Denis Fogarty's crooked line-out throw had conceded a scrum in the home 22.
BBC: Munster 24-10 Ulster
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Leo Cullen was grabbing his chance after his late inclusion in the Irish line-up and his line-out steal from another botched Italian throw set up the game's second try as scrum-half O'Leary sniped over for his first international touchdown.
BBC: Ireland 29-11 Italy